should not put off vaccination.

Other parents said that vaccination would allow them to finally move on from a difficult period of their lives.

In Brookline, Mass., Jenn Erickson, 40, quit her job when her son Miro was born at the start of the pandemic. She has “zero hesitation” about getting him vaccinated, she said, because it would allow her to confidently enroll her son in day care while she returns to work.

“It feels like a lot of the world has moved on without us,” Ms. Erickson said. “The kids who were born during the pandemic are finally getting some protection. There’s going to need to be a massive celebration for the parents who have had to hold this massive stress.”

And for some families, the new vaccine will be life-changing.

Whitney Stohr, 35, of Lynnwood, Wash., planned to take her 4-year-old son, Malachi Stohr-Hendrickson, to get vaccinated on Tuesday at Seattle Children’s Hospital. Malachi has spina bifida, hydrocephalus and congenital heart defects that put him at high risk for complications from Covid-19. For more than two years, the family has stayed isolated.

The shot will mean that Malachi will start in-person occupational and physical therapy and preschool. And since he needs round-the-clock assistance, he will go back to receiving respite care from Ms. Stohr’s mother.

“It’s just going to be a huge sense of relief,” Ms. Stohr said. “It will remove just a deep-seated fear that the virus will get him before we have a chance to try to stop it and try to prevent it.”

Reporting was contributed by Kevin Williams, Christina Capecchi, Ellen B. Meacham, Catherine McGloin, Alanis Thames, Adam Bednar and Hallie Golden.

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