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Cache of 29 Million AstraZeneca Doses in Italy Raises E.U. Suspicions

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BRUSSELS — A stockpile of 29 million doses of AstraZeneca’s Covid-19 vaccine that were found languishing in a facility in Italy became the new flash point on Wednesday in the conflict between the pharmaceutical company and the European Union, as the bloc prepared to unveil stringent export restrictions primarily meant to stop drugmakers from sending doses abroad.

The Italian authorities found the vaccines in a site visit, European Union officials said, at a factory near Rome that is contracted to fill and finish Covid-19 vaccine vials for AstraZeneca.

The Italian authorities went to the site after receiving an alert from the European Commission, which found a discrepancy between what the company said it was producing in European Union facilities, and what the facilities themselves were reporting.

The presence of so many doses raised suspicions that the pharmaceutical company was trying to find a way to export them to Britain or elsewhere, something the bloc has demanded that AstraZeneca stop doing until the company fulfills its promises for deliveries.

daily La Stampa, was bound for Britain. They said the company, when confronted about the doses, said that 16 million doses were bound for the E.U. market and 13 million to countries under the Covax initiative that aims to get doses to poorer nations. Those latter exports would be exempt from E.U. controls, as they are deemed to be of humanitarian nature.

AstraZeneca did not immediately respond to a request for comment.

The officials said they had asked AstraZeneca for additional information about where the active ingredient in the vaccine vials found in Italy had been manufactured — a question aimed at forcing the company to provide more information about its supply chain and production capacity.

For AstraZeneca, the dispute over the Italian doses was the latest in a series of communications blunders with health officials on both sides of the Atlantic that have soured the company’s relationship with several governments.

Some American officials learned about a snag in the company’s clinical trials last year from the news media. The company’s U.S. trial was paused for nearly seven weeks last fall, in part because AstraZeneca was slow to provide American regulators with evidence that the vaccine had not caused a neurological illness. (Investigators later concluded the symptoms were not linked to the vaccine.)

But analysts believe that some of AstraZeneca’s manufacturing difficulties are also a reflection of the company’s ambitious global distribution plans. It had intended to make as many as three billion doses this year, in part by contracting its manufacturing to plants all over the world. Other vaccine makers, by contrast, are relying on only a few facilities.

That global network of factories, analysts said, had the potential to create complications in the company’s supply chain, though it is also part of what has made the vaccine so critical to the global vaccination effort.

Benjamin Mueller contributed reporting from London.

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Filed Under: WORLD Tagged With: AstraZeneca PLC, Australia, Clinical Trials, Coronavirus (2019-nCoV), COVID-19, Drugs (Pharmaceuticals), European Commission, European Union, Exports, Health, Infections, International Trade and World Market, Italy, Media, Production, Shortages, Stockpiling, Vaccination and Immunization

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